Veterinary Drugs

Veterinary drugs are used for therapeutic, metaphylactic, prophylactic and growth promotion purposes. Shimadzu has developed a method using the highly sensitive and selective triple quadrupole mass spectrometer LCMS-8060 together with MRM Spectrum mode to reduce false positive and false negative reporting in multi-residue veterinary drug analysis of food samples such as beef, egg, milk, salmon and more.

Aminoglycosides are an antibiotic family widely used for the treatment of bacterial infections in cattle, sheep, pigs and poultry. Regulatory agencies have set maximum residue limits (MRL) for these compounds after veterinary use. Aminoglycosides are very polar compounds, and usually require the use of undesirable ion-pairing reagents with LC-MS/MS.Shimadzu has developed a Method Package as a complete solution for the simultaneous quantitative analysis of all regulated aminoglycosides by HILIC/MS/MS.

Complete method for fast quantitative screening of 13 aminoglycosides in meat, eggs and milk. Increase identification confidence with MRM Spectrum mode and LabSolutions Insight™ Screening. No ion-pairing reagent required. Includes single sample preparation protocol usable for meat, eggs and milk.

Veterinary drugs are used for therapeutic, metaphylactic, prophylactic and growth promotion purposes. To provide an assurance that food from animals is safe with regards to residues of veterinary medicines, regulatory authorities have established Maximum Residue Limits (MRL's) for certain drugs in target tissues and animal species. Some pharmacologically active compounds identified by regulatory authorities have been prohibited and maximum residue limits in foodstuffs of animal origin have been set in COMMISSION REGULATION (EU) No 37/2010 and published in the last consolidated version of 03/12/2020.

Veterinary pharmaceuticals including antibiotics and hormones are used to prevent disease in livestock, promote growth, and enhance the feed efficiency. Antiparasitic agents are also widely used to eliminate parasites from the alimentary canal. Residual standards are being established for antiparasitic agents as residual levels in meat present similar health problems to antibiotics and hormones. The four components used for this test were 5-hydroxythiabendazole, thiabendazole, flubendazole, and albendazole.

Veterinary drugs are used for therapeutic, metaphylactic, prophylactic and growth promotion purposes. To provide an assurance that food from animals is safe with regards to residues of veterinary medicines, regulatory authorities have established Maximum Residue Limits (MRL's) for certain drugs in target tissues and animal species. Some pharmacologically active compounds identified by regulatory authorities have been prohibited and their hazardousness at all levels are being considered (EU regulation EC 37/2010; Commission Decision 2003/181/EC; 21CFR Part 556 Tolerances for Residues of New Animal Drugs in Food). In this article, we describe how a triple quadrupole mass spectrometer, which is both highly sensitive and selective, contributes to reducing false positive and false negative reporting when using a measurement mode called MRM Spectrum mode.

We consume fish and meat as part of our normal daily diets and healthy human life would be impossible without nutrition from such foodstuffs. Consequently, not only a stable production and supply but safety of farm products, meat, and fish are demanded. Many agricultural chemicals and veterinary pharmaceuticals are currently used to increase productivity, but their residues in food are a problem. This report describes an analysis example of hormones used for livestock. Hormones are used to promote growth in livestock and their safety is investigated in the same way as antibiotics and antiparasitics. The residual standards are established according to the level harmless to humans.