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SBN Webinars

 

Shimadzu Benelux LCMS(MS) Method Development

 

Session 1:

This webinar is designed for people who are new to LC-MS/MS to give them a grounding in the differences from LC before moving onto more in-depth discussions about method development.

 
 
 

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Session 2:

This second session will cover the objectives and strategies to use for successful LC-MS(MS) method development.
For beginners, we suggest you watch Session 1 before attending this session.

 
 
 

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Shimadzu Benelux LC Theory & Key Principles

Session 1: Introduction to Liquid Chromatography

This session will cover:

- What is chromatography and liquid chromatography?
 
- What does an LC column do?
 
- What types of samples can be analysed?
 
- What makes up a Liquid Chromatography instrument?
 
 

Session 1: Introduction to Liquid Chromatography

 

Session 2: Types of LC and Separation Techniques

 

This session will cover:

- Most common types of liquid chromatography

-Effects on compound separation
 

Session 2: Types of LC and Separation Techniques

 

Session 3: The Separation Process, How it is Measured and Improved

This session will cover:

- The process of separation

- How we use peak efficiency, retention, selectivity and resolution to measure the quality of a separation

- What can we do to improve the quality of the separation
 
 
 

Session 3: The Separation Process, How it is Measured and Improved

 

Session 4: Resolution Equation - Applying the Theory in Practice

 

This session will cover:

- Practically improve factors from the resolution equation
 
- Optimise your LC system to improve efficiency
 
- Get the most out of advances in silica particles including superficially porous particles
 
 

 

Session 5: Overview

 

This session will cover:

-  Recap what we have learned in previous sessions
 
-  Ready ourselves for moving onto intermediate liquid chromatography
 

LC Overview

 
 

Session 1: Method Screening

 

This session will introduce:

-  Key considerations to begin method development
 
-  Using Shimadzu's Method Scouting software to screen different mobile phase and stationary phase combinations
 

LC Method Screening

Session 2: Optimising your Method

 

This session will cover:

-  Using retention modelling to generate predictions
 
-  Using ACD Lab LC Simulator to optimise methods
 

LC Optimising your Method

Session 3: Approach to Rectifying Changes in Data

 

This session will introduce:

-  How to overcome data changes
 
-  Look at logical approaches to rectify changes within LC data
 
-  Instrumentation, human, column issues and errors
 

LC Approach to Rectifying Changes in Data

 

Session 1: UHPLC

 
 
 
This session will introduce Ultra High Performance Liquid Chromatography (UHPLC).
 
 
  • How UHPLC can be used to increase efficiency, resolution, sensitivity and thoughput
  • How UHPLC can lessen environmental impact by reducing solvent consumption

UHPLC

Session 2: Advances in Detectors

 
 
 
This session will introduce HPLC/UHPLC Detectors:
 
  • What type of detectors are available 
  • How the modern advances can help our data

Advances in Detectors

Session 3: UHPLC 2

 
 
This session will cover:
 
  • Expand on UHPLC separations 
  • Cover gradient UHPLC

UHPLC 2

Session 4: Advances in Software

 
 
 
Software for all instruments has expanded and changed exponentially since the first LC systems.  Have you ever wondered what those advances are and how they could help you.  This webinar starts the exploration of Software advances by looking at method development, automation and integration.
 
 
 

Advances in Software 

Session 5: Advances in Software part 2

 
 
Software for all instruments has expanded and changed exponentially since the first LC systems.  Have you ever wondered what those advances are and how they could help you.  This webinar starts the exploration of Software advances by looking at method development, automation and integration.
 
 
 

UHPLC

Shimadzu Benelux LC Purification Series

Session 1: Fundamentals of LC Purification

The first session will cover: 

- What is LC purification and how do you get the most out of the technique?

- How much sample can you expect to purify?

- Up-scaling basics

- Recycling and concentration

Watch now 

Session 1: Fundamentals of LC Purification

 

Session 2: Semi-Micro to Analytical Scale LC Purification

This second session will cover:

- Differences between Semi-micro and Analytical Scale Prep

- Principles of the techniques

- Things to consider in semi-micro and analytical scale purification

- Instrumentation and software advantages

Session 2: Semi-Micro to Analytical Scale LC Purification

 

Session 3: Semi-Preparative and other LC Purification Techniques

 

This session will cover:

- Principles, common issues and tips and tricks of Semi-Preparative Chromatography

- UFPLC - Ultra Fast Preparative and Purification LC

- Semi-preparative SFC scale purification

Session 3: Semi-Preparative and other LC Purification Techniques