High-Performance Liquid Chromatograph Mass Spectrometer
Red Dot Design Awards for Product Design 2023
The Shimadzu LCMS-2050 is a next-generation single quadrupole LC-MS system designed to make mass spectrometry accessible, efficient, and reliable for every analytical laboratory. Combining exceptional sensitivity, high-speed analysis, and a remarkably compact footprint, the LCMS-2050 seamlessly integrates with liquid chromatography workflows, delivering superior compound identification and enhanced confidence in analytical results.
Developed for laboratories seeking the advantages of LC-MS detection without the complexity traditionally associated with mass spectrometry, the LCMS-2050 offers a powerful combination of ease-of-use and advanced performance. The system features rapid startup, intuitive operation, and streamlined workflows that reduce training requirements and increase laboratory productivity. Its compact design minimizes laboratory space requirements while maintaining the analytical capabilities expected from a modern mass spectrometer.
The LCMS-2050 delivers outstanding analytical performance with a mass range of m/z 2–2000, scan speeds up to 15,000 u/sec, and rapid 10 ms polarity switching. Advanced ionization technologies, including ESI and APCI (DUIS™), enable highly sensitive detection across a broad range of compounds. This allows laboratories to detect low-level impurities, identify co-eluting compounds, and analyze substances that may not be visible using conventional UV detectors.
One of the system's most innovative features is Mass-it™, a unique function that automatically overlays mass spectrometry data onto chromatograms generated by traditional LC detectors. By combining chromatographic and mass information within a single view, analysts can simplify peak identification, improve data interpretation, and reduce the risk of overlooking critical results. This functionality enhances confidence in compound identification while streamlining routine analysis.
Designed around the concept of "Simply Effortless", the LCMS-2050 focuses on three key benefits: seamless LC integration, superior detection, and cost-efficient operation. The system helps laboratories improve data quality, increase throughput, reduce operational costs, and gain deeper insights from every analysis. Whether used in pharmaceutical research, food safety testing, environmental analysis, chemical characterization, or metabolomics, the LCMS-2050 provides a versatile and future-ready solution for modern analytical challenges.
High-performance liquid chromatography (HPLC) is used extensively across research and industry, to quantify and qualify target compounds. However, its accuracy and sensitivity can be limited when separating compounds with close retention time.
This infographic will demonstrate the impact of mass spectrometry (MS) on HPLC accuracy and efficiency.
UFMS, Nexera, Mass-it, Analytical Intelligence logo, LabSolutions, DUIS, UFscanning, UFswiching and ECO logo are trademarks of Shimadzu Corporation or its affiliated companies in Japan and/or other countries.
LCMS-2050
The LCMS-2050 single quadrupole mass spectrometer combines the user-friendliness of an LC detector with the excellent performance of MS to provide a complete package of easy to use high-level performance and compactness.
LCMS-2050_Live From Analytica 2022
Experience LCMS-2050: The Compact MS with Countless Benefits
How To Change the Desolvation Line on the Single Quad LCMS-2050
This video shows you how easy it is to change the Desolvation Line, or inlet capillary, on Shimadzu’s compact, high-performance single quad LCMS-2050 mass spectrometer.
3 Good health and well-being
2 Zero hunger
6 Clean water and sanitation
Eco Products Plus Certified products
