LCMS-TQ RX Series

Triple Quadrupole LC-MS/MS

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LCMS-TQ RX Series

Ultrafast Track to Your Success

  • Reliable
  • Innovative technology, exceptional design and new ways of thinking are part of our engineering DNA delivering solutions for the ever-changing needs of any laboratory. As our scientific and business needs change our engineering design evolves and adapts. The result is the RX Series of triple quadrupole LC-MS instruments designed with unmatched capability, redefined reliability and creating a new standard in actionable data.

 

LCMS-TQ RX Series – Triple Quadrupole LC-MS Redefined for Reliable Quantitation

The Shimadzu LCMS-TQ RX Series represents the next evolution in triple quadrupole LC-MS/MS technology, delivering unmatched sensitivity, reliability, and operational efficiency for modern analytical laboratories. Designed to address the growing demands of routine and advanced quantitative analysis, the LCMS-TQ RX Series combines innovative hardware, intelligent automation, and robust performance to provide actionable data with confidence. The series is built around Shimadzu’s 3R concept — Reliable, Resilient, and Responsible — helping laboratories achieve consistent results while maximizing productivity. 

The LCMS-TQ RX Series includes the LCMS-8045RX, LCMS-8050RX, and LCMS-8060RX, offering solutions tailored to a wide range of analytical requirements. These high-performance triple quadrupole mass spectrometers build upon the proven success of previous Shimadzu platforms while introducing enhanced stability, improved usability, and advanced ionization technologies. The result is a new standard for quantitative LC-MS/MS analysis in pharmaceutical, environmental, food safety, clinical research, and chemical applications. 

At the heart of the RX Series is the newly developed CoreSpray™ technology, an advanced gas delivery system that enhances nebulization efficiency, heat transfer, and ionization performance. This innovation improves data stability, increases robustness, and supports long-term analytical reliability, even during high-throughput operation. Combined with Shimadzu’s proprietary IonFocus™ technology, available across the RX platform, users benefit from superior sensitivity, improved ion transmission, and highly reproducible quantitative results.

The LCMS-TQ RX Series is designed for laboratories that depend on reliable routine analysis. Intelligent software features and Analytical Intelligence technologies continuously monitor instrument performance, automate maintenance processes, and support users with actionable feedback. Automated diagnostics, performance verification, and tuning assistance reduce operator workload while ensuring optimal system performance and maximum instrument uptime. 

With industry-leading sensitivity, ultra-fast scanning, and exceptional quantitative accuracy, the LCMS-TQ RX Series enables the detection and quantification of trace-level compounds in complex matrices. The platform supports high-throughput workflows while maintaining outstanding data quality, making it ideal for applications ranging from pesticide residue analysis and environmental contaminant monitoring to pharmaceutical bioanalysis and metabolomics research. 

Engineered for today's evolving laboratory environment, the LCMS-TQ RX Series delivers the perfect balance between analytical performance, operational simplicity, and sustainability. By combining innovative ionization technology, intelligent automation, and robust hardware design, Shimadzu has created a triple quadrupole LC-MS platform that empowers laboratories to generate reliable results faster and with greater confidence than ever before. 

 

LCMS-TQ RX Series Line-Up

LCMS-8060RX

LCMS-8060RX

 LCMS-8050RX

LCMS-8050RX

LCMS-8045RX

LCMS-8045RX
The LCMS-8060RX builds on the exceptional sensitivity and UF capabilities of the LCMS-8060NX and adds even more robustness without compromising sensitivity. Engineered to deliver excellent sensitivity the LCMS-8050RX further extends the performance of the LCMS-8050 to meet the ever-changing needs of any LC-MS/MS laboratory. Designed for rugged, routine LC-MS/MS analysis with the optimal balance of cost, sensitivity and performance now enhanced with greater robustness and easier to use.

Features

  • Reliable
    Reliable
    Designed specifically for routine analysis that requires high reliability
  • Resilient
    Resilient
    Trusted performance even with the changing scientific and business needs of laboratories
  • Responsible
    Responsible
    Our drive is to reduce the impact on the environment by designing instruments that work with lower energy and help reduce operating costs

Videos

  • LCMS-TQ RX Series

    Ultrafast track to your success; Shimadzu LCMS-TQ Series are here.
    Reliable: Designed specifically for routine analysis that requires high reliability
    Resilient: Trusted performance even with the changing scientific and business needs of laboratories
    Responsible: Reduced impact on the environment by designing instruments that work with lower energy and reduced operating costs

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