AXIMA Performance – Advanced MALDI-TOF/TOF Mass Spectrometry for High-Confidence Structural Analysis

The Shimadzu AXIMA Performance™ is a research-grade MALDI-TOF/TOF mass spectrometer designed for scientists who require exceptional flexibility, high sensitivity, and powerful structural characterization capabilities. Built around advanced MALDI tandem mass spectrometry (MS/MS) technology, the system delivers high-confidence identification and characterization of peptides, proteins, polymers, glycans, lipids, and other biomolecules. Its unique combination of high-energy collision-induced dissociation (CID) and advanced ion optics makes the AXIMA Performance a powerful solution for life science research and complex molecular analysis. 

At the heart of the AXIMA Performance is a high-energy 20 keV CID-MS/MS system, providing detailed fragmentation patterns for confident structural elucidation. This enables researchers to obtain richer molecular information than conventional MALDI systems, supporting applications such as proteomics, biomarker discovery, lipidomics, polymer characterization, and structural analysis of complex compounds. The high-energy collision environment improves fragment ion generation and supports accurate compound identification. 

The AXIMA Performance incorporates Shimadzu’s proprietary Curved Field Reflectron (CFR) technology, which enhances mass accuracy, sensitivity, and MS/MS performance. Combined with innovative ion-gating technology for precise precursor ion selection, the system ensures high-quality tandem mass spectra while minimizing sample consumption. This allows researchers to perform multiple MS/MS experiments from a single sample spot, maximizing valuable sample utilization. 

Designed for both manual and automated operation, the AXIMA Performance offers flexibility for laboratories of all sizes. Through the LaunchPad™ software suite, users can perform automated data acquisition, peptide mass fingerprinting, protein identification, and complex data analysis workflows. Specialized software modules support a broad range of applications, while optional database searching capabilities streamline compound identification and biological interpretation. 

The system is particularly valuable for proteomics, microorganism identification, glycan analysis, biomarker discovery, polymer characterization, and advanced structural analysis. Researchers benefit from the ability to perform both high-quality MS measurements and detailed MS/MS investigations on a single platform. Its versatility makes it suitable for academic institutions, pharmaceutical research, biotechnology laboratories, and advanced analytical facilities. 

By combining high-energy MALDI-TOF/TOF technology, powerful MS/MS capabilities, advanced reflectron design, and flexible software tools, the AXIMA Performance delivers outstanding analytical confidence for demanding research applications. It remains one of Shimadzu’s most powerful MALDI platforms for laboratories seeking detailed molecular characterization and high-quality tandem mass spectrometry data.