Nexera series
Ultra High Performance Liquid Chromatograph
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Nexera Series – Advanced HPLC and UHPLC Solutions for Modern Laboratories
The Shimadzu Nexera Series sets a new benchmark in high-performance liquid chromatography (HPLC) and ultra-high-performance liquid chromatography (UHPLC). Designed to meet the growing demands of analytical laboratories, the Nexera platform combines cutting-edge analytical performance with intelligent automation, delivering exceptional efficiency, reliability, and reproducibility. The system incorporates innovative technologies such as Artificial Intelligence (AI), Internet of Things (IoT) connectivity, self-diagnostics, and automated monitoring to maximize laboratory productivity and ensure consistent analytical results.
Available in configurations ranging from 440 bar to 1,300 bar, the Nexera Series offers unparalleled flexibility for routine HPLC analyses as well as the most demanding UHPLC applications. Advanced features such as mobile phase monitoring, FlowPilot technology, automated startup and shutdown, remote monitoring, and self-recovery functions help reduce downtime and support uninterrupted operation. The modular architecture allows laboratories to tailor the system to specific analytical requirements while maintaining future expandability.
The Nexera Series is engineered to provide outstanding chromatographic performance with high retention time reproducibility, ultra-low carryover, precise sample injection, and high-sensitivity detection. A broad range of detectors, including UV-Vis, PDA, fluorescence, refractive index, conductivity, ELSD, and mass spectrometry, enables accurate analysis across pharmaceutical, environmental, food, chemical, and life science applications.
By integrating Analytical Intelligence and advanced automation, the Nexera Series simplifies workflows, minimizes user intervention, and improves laboratory efficiency. Whether performing routine quality control or advanced research analyses, laboratories can benefit from enhanced throughput, reliable data quality, and reduced operational costs. The Nexera Series truly represents the future of liquid chromatography technology.
Nexera series Lineup

Features
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Automated support functions utilizing digital technology, such as M2M, IoT, and Artificial Intelligence (AI), that enable higher productivity and maximum reliability.
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Allows a system to monitor and diagnose itself, handle any issues during data acquisition without user input, and automatically behave as if it were operated by an expert.
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Supports the acquisition of high quality, reproducible data regardless of an operator’s skill level for both routine and demanding applications.
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Latest Webinar
Videos
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Nexera series
- Experience New Benchmarks - The Nexera series is a family of HPLC systems that marries AI and IoT enhancements to set new industry
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Nexera series Concept Video
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Evaluating Technical Proficiency of ADRA Skin Sensitization
Evaluating Technical Proficiency of ADRA Skin
Sensitization Testing and High Speed Analysis
It can meet the standards of the proficiency assessment test and the system suitability test of the ADRA test method, which is one of the skin sensitization tests to assess the allergy of chemicals to the skin. It also allows for quick analysis.
