Shim-pack Velox C18

HPLC Column

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Shim-pack Velox C18

Shimadzu Shim-pack Velox C18: Precision and Performance in HPLC

The Shimadzu Shim-pack Velox C18 column is specifically designed to enhance the performance of high-performance liquid chromatography (HPLC) applications. Renowned for its exceptional separation capabilities and reliability, this column is ideal for a wide range of analyses in pharmaceuticals, environmental monitoring, and food safety.

Key Features of the Shimadzu Shim-pack Velox C18

  1. High Separation Efficiency: The Velox C18 column utilizes advanced packing technology that ensures superior separation efficiency. This results in high-resolution chromatograms, even for complex mixtures.

  2. Versatile Application Range: Designed to handle both polar and non-polar compounds, the Shim-pack Velox C18 is suitable for various applications, making it an essential tool for any analytical laboratory.

  3. Durable and Reliable Construction: Built with high-quality materials, the Velox C18 is engineered for durability, providing consistent performance and reducing the frequency of column replacements.

  4. Easy Integration: The Shim-pack Velox C18 is compatible with a variety of HPLC systems, allowing for seamless integration into existing laboratory setups, thus enhancing workflow efficiency.

C18

Shim-pack Velox C18 is a traditional end-capped C18-bonded phase which offers the highest hydrophobic retention of any Shim-pack Velox phases and is applicable to a wide range of applications such as pharmaceutical, food, environmental and clinical and neutrals at moderately low and mid-range pH.

  • General purpose column for reversed-phase chromatography
  • Highest hydrophobic retention among Shim-pack Velox series
  • Compatible with moderately acidic to neutral mobile phases (pH 2-8)

Method Transfer for Cyanocobalamin Analysis within the USP Allowable Adjustment

The assay of cyanocobalamin (a synthetic form of vitamin B12) with 5 μm fully-porous ODS column described in the USP monograph is transferred to a new method with Shim-pack Velox C18 2.7 μm column, within USP allowable adjustments. Analytical time and solvent consumption can be saved with transferred methods while meeting the requirements of system suitability.

 

 

 

 

 

 

Column L/dp Flow rate
(mL/min)		 N System suitability test result
(Requirement: %RSD < 2.0 %)
VP-ODS
(5 μm, 4.6 x 150 mm)		 30,000 0.50 5,244 tR: 0.025 %
Area: 0.175 % (n=6)
 
Velox C18
(2.7 μm, 4.6 x 100 mm)
 
37,037
(+23 %)
 0.50 9,497
(+81 %)		 tR: 0.035 %
Area: 0.103 % (n=6)
0.93 4,466
(-15 %)		 tR: 0.084 %
Area: 0.220 % (n=6)
 

 

 

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