MALDI-8020
Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometer
MALDI-8020 – Compact MALDI-TOF Mass Spectrometry for Fast and Reliable Analysis
The Shimadzu MALDI-8020 is a compact benchtop MALDI-TOF mass spectrometer designed to deliver fast, accurate, and reliable mass measurements for a wide range of analytical applications. Combining a small footprint with robust performance, the MALDI-8020 provides an accessible solution for laboratories performing routine quality control, biomolecule analysis, polymer characterization, and research workflows. The system offers the analytical power of MALDI-TOF technology without the complexity or space requirements of larger mass spectrometry platforms.
The MALDI-8020 operates as a linear positive-ion MALDI-TOF system and is equipped with a high-performance 200 Hz solid-state laser that enables rapid sample analysis and high throughput. Fast sample introduction via an integrated load-lock chamber minimizes downtime between analyses, helping laboratories increase productivity while maintaining excellent analytical performance.
Designed with ease of use in mind, the system incorporates several innovative technologies that simplify operation and reduce maintenance. Patented TrueClean™ UV laser source cleaning helps minimize source contamination, while Wide Bore™ ion optics improve sensitivity and contribute to long-term instrument stability. The robust benchtop design, low maintenance requirements, and quiet operation make the MALDI-8020 an ideal choice for both experienced mass spectrometry users and laboratories new to MALDI analysis.
The MALDI-8020 supports the analysis of a diverse range of sample types, including proteins, peptides, oligonucleotides, polymers, lipids, glycans, and small molecules. With a mass range up to m/z 500,000, the instrument provides the flexibility required for both routine measurements and advanced research applications. Its excellent mass resolution and mass accuracy support reliable compound characterization and molecular weight determination.
The instrument is controlled through MALDI Solutions™ software, which provides a secure, user-friendly environment for data acquisition and analysis. Features such as user account management, configurable user permissions, barcode integration, raster scanning, and automated sample handling support efficient workflows and improved sample traceability.
For laboratories seeking additional flexibility, the MALDI-8020 can be expanded with optional imaging capabilities and automation solutions. Imaging upgrades, automated sample preparation tools, and high-throughput accessories allow researchers to extend the capabilities of the platform as analytical requirements evolve.
Whether used in pharmaceutical research, proteomics, polymer analysis, clinical screening, quality control, or academic research, the MALDI-8020 provides a cost-effective and highly reliable platform for rapid MALDI-TOF mass spectrometry. By combining compact design, powerful performance, and user-friendly operation, it delivers an efficient solution for laboratories seeking routine and advanced molecular analysis.
Example of a 4.2 kDa peptide demonstrating an average resolution of >5000 FWHM. Resolution, calculated by the software, is shown in brackets.
Linear mode instruments have traditionally been the instruments of choice in MALDI-TOF-based quality control (QC) and profiling workflows, and the MALDI-8020 is no exception. Peptides, proteins, polymers or oligonucleotides - the instrument is capable of delivering the performance required for QC applications. Research laboratories will also benefit from the MS capabilities of the instrument through the rapid mass-measurement of samples.
* For Research Use Only. Not for use in diagnostic procedures.
Features
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Compatible with the FlexiMass™ series of microscope slide-format sample targets, these slides provide researchers with options depending on their experimental workflow...
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To maintain instrument performance over time, the MALDI-8020 features wide-bore ion optics - a feature used on our existing MALDI-TOF products - which minimize the risk of source contamination over time, providing a robust platform...
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Operating under the control of MALDI Solutions™ software, the software features a centralized, secure Microsoft® SQL database which can be used to store everything from sample lists and acquisition Parameter Sets to acquired MALDI data...
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As mass spectrometry moves into clinical laboratories, the MALDI-8020 is the perfect choice for researchers developing MALDI-based diagnostic methods*. The system is designed and manufactured to ISO 9001:2015 and ...
Videos
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MALDI-8020 Loading and Operation
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MALDI 8020 Benchtop Linear MALDI-TOF Mass Spectrometer
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Benchtop MALDI-TOF Imaging Starter Kit
Compact, Affordable, MALDI Imaging: the application of Mass Spectrometry imaging is rapidly growing but is still only utilised by experienced scientists.
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Rapid and Simple Sequence Confirmation of Nucleic Acid Therapeutics : MALDI
A MALDI-8020 benchtop MALDI-TOF mass spectrometer enabled a rapid measurement with simple sample preparation.
The instrument supports a rapid and easy sequence confirmation of nucleic acid therapeutics.